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幹細胞・分化・発生生物学

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TPX2 prompts mitotic survival via the induction of BCL2L1 through YAP1 protein stabilization in human embryonic stem cells

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Dextran sulfate prevents excess aggregation of human pluripotent stem cells in 3D culture by inhibiting ICAM1 expression coupled with down-regulating E-cadherin through activating the Wnt signaling pathway.

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Characterization of Human Bone Marrow Niches with Metabolome and Transcriptome Profiling

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ANT2 drives proinflammatory macrophage activation in obesity

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In Vivo Cell Fate Tracing Provides No Evidence for Mesenchymal to Epithelial Transition in Adult Fallopian Tube and Uterus

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The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes

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Expression of polo-like kinase 1 in pre-implantation stage murine somatic cell nuclear transfer embryos

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Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation

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Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

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Muscle-secreted granulocyte colony-stimulating factor functions as metabolic niche factor ameliorating loss of muscle stem cells in aged mice

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Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics

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Two-Cell Spheroid Angiogenesis Assay System Using Both Endothelial Colony Forming Cells and Mesenchymal Stem Cells

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Mesenchymal stem cells of Oravka chicken breed: promising path to biodiversity conservation

幹細胞・分化・発生生物学
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癌・腫瘍生物学

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E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry

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The Effect of Activated FXIII, a Transglutaminase, on Vascular Smooth Muscle Cells

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Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress

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Yes-Associated Protein Is Required for ZO-1-Mediated Tight-Junction Integrity and Cell Migration in E-Cadherin-Restored AGS Gastric Cancer Cells

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Expression of E-Cadherin in Epithelial Cancer Cells Increases Cell Motility and Directionality through the Localization of ZO-1

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Single-cell tracking reveals super-spreading brain cancer cells with high persistence.

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ERK Dephosphorylation through MKP1 Deacetylation by SIRT1 Attenuates RAS-Driven Tumorigenesis

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Establishment and Characterization of a Brca1--, p53-- Mouse Mammary Tumor Cell Line

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Activation of the Ion Channel TRPV4 Induces Epithelial to Mesenchymal Transition in Breast Cancer Cells

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Single-cell tracking reveals super-spreading cells with high persistence in invasive brain cancer

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ORAI1 and ORAI3 in Breast Cancer Molecular Subtypes and the Identification of ORAI3 as a Hypoxia Sensitive Gene and a Regulator of Hypoxia Responses

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Schedule-dependent potentiation of chemotherapy drugs by the hypoxia-activated prodrug SN30000

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PAR-2 promotes invasion and migration of esophageal cancer cells by activating MEK/ERK and PI3K/Akt signaling pathway

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c-Myc shuttled by tumour-derived extracellular vesicles promotes lung bronchial cell proliferation through miR-19b and miR-92a

癌・腫瘍生物学
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薬理・毒性・創薬

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Comparison of Different Clinical Chemotherapeutical Agents’ Toxicity and Cell Response on Mesenchymal Stem Cells and Cancer Cells

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Preventive effects of the butanol fraction of Justicia procumbens L. against dexamethasone-induced muscle atrophy in C2C12 myotubes

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Synthesis and Preliminary Anticancer Activity Assessment of N-Glycosides of 2-Amino-1,3,4-thiadiazoles.

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Synthetic Retinoid Seletinoid G Improves Skin Barrier Function through Wound Healing and Collagen Realignment in Human Skin Equivalents

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Zinc and Iron Homeostasis: Target-Based Drug Screening as New Route for Antifungal Drug Development

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Structure-Activity Relationship Analysis of YM155 for Inducing Selective Cell Death of Human Pluripotent Stem Cells

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Screening of cytotoxic or cytostatic flavonoids with quantitative Fluorescent Ubiquitination-based Cell Cycle Indicator-based cell cycle assay

薬理・毒性・創薬
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バイオマテリアル・ナノテクノロジー

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Multifunctional Nanocrystalline Cu-Ti Thin Films Enhance Survival and Induce Proliferation of Mouse Fibroblasts In Vitro.

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29.Extracellular Matrix Proteins and Substrate Stiffness Synergistically Regulate Vascular Smooth Muscle Cell Migration and Cortical Cytoskeleton Organization. ACS Publications , 2020

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Multimodal mesoporous silica nanocarriers for dual stimuli-responsive drug release and excellent photothermal ablation of cancer cells

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Physical Properties and Biofunctionalities of Bioactive Root Canal Sealers In Vitro

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A facile hydrothermal synthesis of highly luminescent upconversion nanoparticles and their biomonitoring capability

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Magnetically Assisted Control of Stem Cells Applied in 2D, 3D and In Situ Models of Cell Migration

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Synthesis of fluorescent silicon quantum dots for ultra-rapid and selective sensing of Cr(VI) ion and biomonitoring of cancer cells

バイオマテリアル・ナノテクノロジー
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免疫・炎症・感染症

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Resistance of Blastocystis to chlorine and hydrogen peroxide

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Dichotomous role of Shp2 for naïve and primed pluripotency maintenance in embryonic stem cells

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MiR-519d-3p in Trophoblastic Cells: Effects, Targets and Transfer to Allogeneic Immune Cells via Extracellular Vesicles

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Extracellular DNA traps in a ctenophore demonstrate conserved immune cell behaviors in a non-bilaterian

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Maternal high-fat diet exaggerates diet-induced insulin resistance in adult offspring by enhancing inflammasome activation through noncanonical pathway of caspase-11

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Role of IL-36 Cytokines in the Regulation of Angiogenesis Potential of Trophoblast Cells

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An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness

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Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response

免疫・炎症・感染症
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神経・筋・生理学

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Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism

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Ctenophore extracellular DNA traps demonstrate conserved antimicrobial behaviors present at the emergence of animals

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Rapid and Efficient Generation of Myelinating Human Oligodendrocytes in Organoids

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Ninjurin 1 dodecamer peptide containing the N-terminal adhesion motif (N-NAM) exerts proangiogenic effects in HUVECs and in the postischemic brain

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Fine Tuning of Calcium Constitutive Entry by Optogenetically-Controlled Membrane Polarization: Impact on Cell Migration

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Nuclear connectin novex-3 promotes proliferation of hypoxic foetal cardiomyocytes

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Methamphetamine and Designer Stimulants Modulate Tonic Human Cerebrovascular Smooth Muscle Contractility

神経・筋・生理学
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計算・解析・手法開発

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Study on the Expansion Dynamics of MDCK Epithelium by Interstitial Flow Using a Traction Force-Measurable Microfluidic Chip

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Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis

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An integrated pipeline for high-throughput screening and profiling of spheroids using simple live image analysis of frame to frame variations

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Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements

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An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids

計算・解析・手法開発
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